Recurrent episodes of viral croup in children: potential causes and approaches to its prevention

Viral croup is one of the most common causes upper respiratory tract obstruction in children under 6 years age. Frequent acute infections (ARIs) and a burdened history allergies might be triggers for recurrent episodes viral croup. Purpose — to study vitamin D status infants with efficacy cholecalciferol supplements prevention. Materials methods. Hospital(based survey included 128 aged 4–36 months Vitamin was evaluated by measuring serum 25 (OH) levels. Control studies were performed after 12 weeks. A prospective follow(up lasted three years. Results. 32.8±4.1% (42/128) hospitalized had frequent ARIs (>6 per year). Recurrent more compared those who did not have 46.4±9.4% (13/28) vs. 23.0±4.2% (23/100) (?=0.028). At time enrollment, 47.6±4.4% (61/128) optimal concentration (??) (30–100 ng/ml). Serum levels regularly received 33.5 ng/ml (27.2–44.5) at control. Patients level D>30 less likely (0/29) during observation period 20–30 (25.0±10.8%, 4/16) (p=0.023). In ng/ml, risks future 9 times lower (OR=9.00; 95% CI: 1.55–52.27), mild course 11.4 (OR=11.40; 1.20–108.29). Conclusions. Insufficient recorded 46.1±4.4% When increased >30 frequency decreased (p=0.023); decreased, as well severe course. The research carried out accordance principles Helsinki Declaration. protocol approved Local Ethics Committee all participating institution. informed consent patient obtained conducting studies. No conflict interest declared author. Key words: episodes, croup, children, causes,